Fill out this form to download.

Fill out this form to get started.

Image showing DW Fritz designed precision fixturing and nozzle geometry to ensure nanoliter-level dispensing of fluids onto a substrate in medical device manufacturing.

Precision Dispensing Automation for Complex Manufacturing Applications

Executive Summary

Automating precision dispensing processes presents unique challenges in high-performance manufacturing environments, especially when tolerances are tight, volumes are high, and materials are difficult to control. Precision dispensing automation refers to the controlled, repeatable application of fluids or adhesives at micron- or nanoliter-scale accuracy within an automated production system.

DWFritz applies a first-principles engineering approach to complex dispensing applications, combining risk mitigation, design-for-manufacturing methodology, and tightly integrated systems to ensure production-ready performance. This article explores the technical considerations, real-world challenges, and automation strategies required to successfully deploy precision dispensing solutions in medical device and consumer product manufacturing.

Why Precision Dispensing Is Difficult to Automate

Automating dispensing processes is inherently complex. Small variations in material properties, temperature, part geometry, or cleanliness can significantly affect process outcomes. These challenges are amplified in high-volume or high-precision manufacturing environments.

Common challenges include:

Solving these challenges requires more than selecting a dispense valve. It requires a system-level approach.

High-precision dispense of nanoliter volumes of varying viscosity pharmaceuticals.
High-precision dispense of nanoliter volumes of varying viscosity pharmaceuticals.

Reducing Risk Through Early Technology Validation

DWFritz prioritizes risk mitigation early in the project lifecycle to ensure technical feasibility and performance confidence.

We conduct:

This work is performed both internally and with third-party vendors using customer-specific materials and geometries. Early validation reduces downstream investment risk, compresses development timelines, and prevents late-stage redesigns.

In-house PoP and performance benchmarking of a Nordson commercial dispense solution on a DWFritz test bed machine.

Designing for Manufacturing from the Start

Design for Manufacturing (DFM) is the practice of designing products and processes in a way that simplifies automation, improves yield, and reduces total system cost.

Automation is often considered late in product development. When manufacturing strategy and automation design are addressed early, significant gains can be achieved.

Example: Energy Storage Assembly

In an energy storage application, thermal adhesive was being extruded from the bond joint between battery cell and cooling system during compression, resulting in insufficient bond thickness. Rather than adding costly fixturing, DWFritz recommended incorporating controlled-diameter glass media into the epoxy. This established a precise bond line thickness without additional alignment hardware, reducing cost and improving repeatability.

Taking a Holistic Systems Approach

Dispensing performance depends on the interaction of multiple subsystems, not just the dispense valve itself.

High-performing dispense automation requires:

Treating dispensing as a standalone operation introduces risk. Treating it as a fully integrated system enables reliability and scalability.

Ensuring Needle Cleanliness and Process Availability

Dispense tip contamination is a major source of downtime and quality issues.

Risks include:

Medical Device Use Case

For a high-OEE medical device assembly system, DWFritz integrated a commercial wiping mechanism and developed a machine vision tool to inspect the needle after every dispense. When excess adhesive was detected, the system automatically executed a cleaning and priming sequence that recovered up to 5 minutes of runtime per hour and improved ROI by up to 8%.

Controlling Dispense Tip Temperature

The viscosity of adhesives, lubricants, and pharmaceutical fluids is highly sensitive to temperature variation. Even small ambient changes can destabilize a process.

DWFritz integrates:

This approach stabilizes dispensing performance across seasonal and environmental conditions, particularly in medical device, and consumer electronics wearable and handheld manufacturing.

Achieving Mass Accuracy Through Closed-Loop Control

To ensure consistent shot weight, DWFritz integrates high-precision analytical balances directly into automated dispense systems.

This enables:

The result is deterministic control without operator intervention.

Managing Part Motion and Active Alignment

In ultra-small dispense applications, part and tool variation can exceed the dispense volume itself.

Medical Device Example

Applying ~35 nL of adhesive around a 1.5 mm diameter part required compensating for tolerance stack-ups larger than the bead height. DWFritz used metrology-class machine vision, custom lighting, and a high-precision multi-axis servo system to actively align every part, maintaining runout below 25 µm and enabling consistent application.

Using non-contact 3D metrology for volume measurement of nanoliter scale adhesive droplets. Center to center pitch of 1.5mm for scale.

Integrating Cure and Cure Fixturing

Dispensing success doesn’t end at application. Cure behavior and part constraint during cure are equally critical.

DWFritz designs:

Software enforcement ensures parts meet time- and temperature-based cure requirements before downstream handling.

Frequently Asked Questions

What makes precision dispensing difficult to automate?

Small variations in temperature, material behavior, and alignment can dramatically affect outcomes at micron- and nanoliter-scale dispensing.

Why is early PoC testing important?

It validates feasibility using real materials and geometries, reducing downstream risk and cost.

Can dispensing systems maintain high throughput and precision?

Yes—when dispensing is treated as a system-level challenge incorporating motion, vision, software, and fixturing.

Glossary of Key Terms

Precision dispensing: Automated application of fluids or adhesives with tightly controlled volume, placement, and repeatability.

Design for Manufacturing (DFM): Designing products and processes to simplify automation, reduce cost, and improve yield.

OEE (Overall Equipment Effectiveness): A metric measuring availability, performance, and quality in production systems.

2K adhesive: A two-part adhesive that cures through chemical reaction after mixing.

Machine vision: Image-based inspection and measurement systems used for alignment and quality verification.